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KMID : 1037020170060020077
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Medical Lasers; Engineering, Basic Research, and Clinical Application
2017 Volume.6 No. 2 p.77 ~ p.85
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A Treatment of Medium-to-Giant Congenital Melanocytic Nevi with Combined Er:YAG Laser and Long-Pulsed Alexandrite Laser
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Hong Kyung-Tae
Lim Jung-Min
Lee Sang-Eun
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Abstract
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Background and Objectives: Lasers are alternative methods of treatment for congenital melanocytic nevi (CMN) located on cosmetically sensitive or surgically challenging areas. Long-pulsed pigment lasers can show greater efficacy than Q-switched lasers in destroying nevomelanocytic nests, and partial epidermal ablation by Er:YAG lasers allow pigment lasers to penetrate deeper into the skin. In this study, we evaluated the efficacy of combined Er:YAG and long-pulsed alexandrite (LP-Alex) laser treatment for medium to giant CMN.
Materials and Methods: Six patients were enrolled. All nevi were treated with combined Er:YAG and LP-Alex lasers at an interval of 9?12 weeks. Persistent erythema was further treated using long-pulsed dye lasers (LPDL).
Results: All medium CMN showed good-to-excellent pigment removal after 1.83 sessions of combined laser treatment. Giant CMN showed good pigment removal after a single treatment. No severe textural changes, hypertrophic scars, or depigmentation were observed. Moderate hypertrophic scarring was revealed in one patient; mottled hypopigmentation was observed in one patient; and persistent erythema was noted in two patients, which decreased with further LPDL treatment. Repigmentation or malignant transformation was not observed during the follow-up period of 2?9 months.
Conclusion: Combined Er:YAG and LP-Alex laser treatment appears to be effective for removing medium-to-giant CMN with minimal adverse effects.
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KEYWORD
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Congenital melanocytic nevi, Er:YAG Laser, Long-pulsed Alexandrite Laser
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